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Cajun Beef Jerky

This Cajun Beef Jerky recipe will excite your taste buds! With flavors that come straight from New Orleans, you can’t go wrong with this tasty recipe!

A Cajun Spiced Beef Jerky that will excite your taste buds! Easy to make jerky that's packed with protein. | Jerkyholic.com

A lot of my recipes come about by searching the internet, cook books, restaurant dished, etc. This one came from several Cajun marinades and seasonings I found while looking through some cook books. The flavors turned out great and work very well with beef jerky.

I love using Beef Eye of Round when making jerky and that is what I used when making this batch. The strips were sliced with the grain giving this Cajun Beef Jerky some good chew.

Eye of Round Sliced with the Grain

Several years ago I lived in New Orleans for a little while and LOVED the food there. I love spice and that is exactly what Cajun food is known for.

I didn’t like the heat and humidity of the city, but sometimes you have to sacrifice to eat good food!

The cayenne pepper, seasoning salt, and paprika just go so well with the vinegar based marinade.

Cajun Beef Jerky SlicedI mixed up all the ingredients well and marinated the beef for 20 hours in the fridge. Anywhere between 6 – 24 hours of marinating time will be just fine.

Cajun Beef Jerky Drained

After patting the strips dry with a paper towel, dry using your favorite jerky making method. These bad boys were dried using my Nesco Dehydrator for about 5 hours.

Cajun Beef Jerky on TraysThis Cajun Beef Jerky had a spicy kick with a great herb taste from all the thyme and oregano. I really liked how this recipe turned out.

So if you are looking for a taste of New Orleans and ready for a little spice in your life, you NEED to make a batch of this Cajun Beef Jerky! Let me know how yours turns out in the comments below!

Cajun Beef Jerky with all the heat and spice of New Orleans! | Jerkyholic.com

For more in depth directions on how to dry your beef jerky, visit my page Jerky Making Methods or click on the pictures below.

How to make Beef Jerky in the OvenLearn how to make Beef Jerky in a dehydrator. It's easy, fast, and delicious! | Jerkyholic.comLearn how to make beef jerky in a smoker. Great tasting and better than store bought jerky! | Jerkyholic.com

4.0 from 1 reviews
Cajun Beef Jerky
Prep time
Cook time
Total time
Lean Meat
  • ½ cup cold water
  • ¼ cup white vinegar
  • ½ tsp garlic powder
  • 1 tsp oregano
  • 1 tsp thyme
  • 1 tsp seasoning salt
  • 2 tsp cayenne pepper
  • 1 tsp paprika
  • 1 tsp black pepper
  • 1 tsp horseradish
  • ½ tsp red pepper flakes
  1. Trim all visible fat from the beef and place in freezer for an hour or two to partially freeze.
  2. While the meat is in the freezer, combine the white vinegar, cold water, garlic powder, oregano, thyme, seasoning salt, cayenne pepper, paprika, black pepper, horseradish, and red pepper flakes in a bowl or ziplock bag and mix well.
  3. Remove the meat from the freezer and slice ¼" strips against the grain for an easy chew. Cut with the grain for more chew. Or skip the freezing phase and use a Jerky Slicer for even sliced strips.
  4. Add sliced beef to the mixture in a ziplock bag or bowl and marinate for 8-24 hours in the refrigerator.
  5. After the meat has finished marinating, remove from refrigerator and strain excess marinade and pat dry the beef strips with paper towels
  6. Dry with your favorite jerky making method. I used my dehydrator and dried for 5 hours at 160 degrees.
  7. The jerky is finished when it bends and cracks, but does not break in half.

For more in depth directions on how to dry your beef jerky, visit my page Jerky Making Methods


  1. David says:

    I put a thin coat of BBQ sauce on the jerky and then sprinkled cajun seasoning on it before putting it in the dehydrator. Great flavor

  2. Beverley says:

    Hola will

    I’m a newbie. I’m heading up to the states to California to get my dehydrator so I can start making jerky. I haven’t seen any here in Baja so I’m going to give it a shot
    I have a question I see that you have the Prague Powder as optional can you explain why it’s option and what it does to enhance the flavors and when do you use it in the recipe. For example I was reading one of the recipes and you had it as optional but in the instructions you didn’t mention when you should add this I’m assuming(but you know what they say about assuming) that it’s added (if you wanted) to the marinade mix. Is this correct?

    Thanks for all the great recipes I am excited about adding this to all my other cooking methods…. canning veggie/fruit growing baking and cooking…. I sell all my products here and I’ve had many that ask me if I make jerky. My answer not yet but soon. Plus I want to make dog jerky treats too
    Do you think that I could marinate the beef in my homemade bourbon bacon bbq sauce then dehydrate it and is there one ingredient that you always need to use when making jerky or is anything you want to marinate your meat in and the hydrate. I warned you I’m a newbie. Lol
    Thank you and hope you and your family are having an amazing day

    • Will
      Will says:

      Hey Beverley! The curing salt is optional because as long as you heat the jerky to 160F it will be safe to eat. However, curing salt will make sure the jerky is safe as well as make it last longer. It adds that red color you see in most jerky and other cured meats and has a distinct flavor which is synonymous with beef jerky. When using cure, add it along with the other ingredients of the marinade. I think your bourbon bacon bbq sauce sounds like it will make an AMAZING beef jerky!!! You can use ANY ingredient when making jerky but one that is normally found in all jerky is salt, it helps preserve the meat. Let me know how your jerky turns out!

  3. Richard Baker says:

    I want to make beef jerky which is spicy. Which kind of marinade would work well to accomplish this? I have just marinaded meat before, using Worcester, cayenne pepper, a little liquid smoke, and salt. Do you have a professional marinade which would work better? Thank you for all your advice.

    • Will
      Will says:

      Hey Stacey! Thanks for trying this recipe, I’m sorry you guys didn’t like it… I hope you give some other recipes a try. You just have to find the ones you guys really like!

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